487 research outputs found

    Cancer Biology Data Curation at the Mouse Tumor Biology Database (MTB)

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    Many advances in the field of cancer biology have been made using mouse models of human cancer. The Mouse Tumor Biology (MTB, "http://tumor.informatics.jax.org":http://tumor.informatics.jax.org) database provides web-based access to data on spontaneous and induced tumors from genetically defined mice (inbred, hybrid, mutant, and genetically engineered strains of mice). These data include standardized tumor names and classifications, pathology reports and images, mouse genetics, genomic and cytogenetic changes occurring in the tumor, strain names, tumor frequency and latency, and literature citations.

Although primary source for the data represented in MTB is peer-reviewed scientific literature an increasing amount of data is derived from disparate sources. MTB includes annotated histopathology images and cytogenetic assay images for mouse tumors where these data are available from The Jackson Laboratory’s mouse colonies and from outside contributors. MTB encourages direct submission of mouse tumor data and images from the cancer research community and provides investigators with a web-accessible tool for image submission and annotation. 

Integrated searches of the data in MTB are facilitated by the use of several controlled vocabularies and by adherence to standard nomenclature. MTB also provides links to other related online resources such as the Mouse Genome Database, Mouse Phenome Database, the Biology of the Mammary Gland Web Site, Festing's Listing of Inbred Strains of Mice, the JAX® Mice Web Site, and the Mouse Models of Human Cancers Consortium's Mouse Repository. 

MTB provides access to data on mouse models of cancer via the internet and has been designed to facilitate the selection of experimental models for cancer research, the evaluation of mouse genetic models of human cancer, the review of patterns of mutations in specific cancers, and the identification of genes that are commonly mutated across a spectrum of cancers.

MTB is supported by NCI grant CA089713

    Creating Teaching Opportunities for STEM Future Faculty Development

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    Graduate school is an important time for future faculty to develop teaching skills, but teaching opportunities are limited. Discipline-related course work and research do not provide the pedagogy, strategies, and skills to effectively teach and compete for higher education jobs. As future faculty, graduate students will influence the future of science, technology, engineering, and mathematics (STEM) education through their teaching. The purpose of this case study was to examine future faculty’s (graduate students’) perceived teaching development during a semester-long STEM teaching development course. Findings included STEM future faculty’s teaching confidence and skill development in instructional design, preparation, and facilitation; greater development in skill awareness than student awareness and self-awareness; and a focus on knowledge-centered learning environments for future classroom teaching experiences

    The i-School movement

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    No Abstract.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/57317/1/14504301131_ftp.pd
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